International Review of Ophthalmology

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Advances in the treatment of ocular surface diseases by amniotic membrane

Li Nanyu, Zhang Wenjia, Hu Zhulin   

  1. The Fourth Affiliated Hospital of Kunming Medical University, Kunming Medical University, Yunnan Eye Institute, Key Laboratory of Yunnan Province for the Prevention and Treatment of Ophthalmology, Provincial Innovation Team for Cataract and Ocular Fundus Disease, Expert Workstation of Yao Ke, Kunming 650000, China
  • Received:2018-11-04 Online:2019-04-25 Published:2019-04-30
  • Contact: Hu Zhulin, Email: hu-zhulin@163.com
  • Supported by:

    Science and Technology Project\|Major Project of Yunnan Province (2018ZF009)；Key Laboratory of Yunnan Province for the Prevention and Treatment of ophthalmology(2017DG008); Provincial Innovation Team for Cataract and Ocular Fundus Disease, The Second People’s Hospital of Yunnan Province(2017HC010); Expert Workstation(2017IC064); Yunan Medical and Scientific Development Program (2016NS182)

Abstract:

Amniotic membrane is a common auxiliary material used in the treatment of eye diseases. With the development of tissue engineering, new amniotic membrane preparations based on amniotic membrane (such as amniotic membrane eye drops, cross\|linked amnion, drug amnion and amniotic cell culture vectors) not only retain the histopathological characteristics of amnion (such as low immunogenicity, promotion of epithelial formation, anti\|fibrosis and anti\|inflammatory, anti\|angiogenesis, antibacterial, etc.), also confers new and excellent characteristics of amniotic membrane, making amniotic membrane more convenient and effective in the treatment of ocular surface diseases(such as acute or chronic chemical eye burns, persistent epithelial defect, foamy keratopathy, corneal and scleral ulcer, etc.), showing a broad prospects for clinical application.   (Int Rev Ophthalmol, 2019, 43:  94-99)